Nigracin Chemical Properties

Melting point:

205 °C (decomp)

Boiling point:

677.6±55.0 °C(Predicted)

Density 

1.485±0.06 g/cm3(Predicted)

storage temp. 

-20°C

pka

9.92±0.20(Predicted)

form 

solid

biological source

plant

Nigracin Usage And Synthesis

Uses

It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical and biochemical research.

Biological Activity

Poliothyrsoside is a pyruvic transaminase inhibitor known for its insulin-sensitizing effects in cell culture. Additionally, it exhibits anti-diabetic properties by inhibiting acetyl-CoA carboxylase, ultimately enhancing insulin sensitivity and lowering blood glucose levels in diabetic mice. This compound also serves as a lactate dehydrogenase inhibitor and demonstrates antidepressant-like actions, along with effectiveness against Alzheimerμs disease. In vitro studies have further revealed Poliothyrsosideμs capacity to inhibit virus production and exhibit antiviral activity against HIV-1.

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