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N-p-trans-Coumaroyltyramine

Basic information Safety Supplier Related

N-p-trans-Coumaroyltyramine Basic information

Product Name:
N-p-trans-Coumaroyltyramine
Synonyms:
  • N-p-trans-Coumaroyltyramine
  • N-p-CouMaroyltyraMine
  • 2-Propenamide, 3-(4-hydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-, (2E)-
  • (2E)-3-(4-Hydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide
  • (E)-N-(4-Hydroxyphenethyl)-3-(4-hydroxyphenyl)acrylamide
CAS:
36417-86-4
MF:
C17H17NO3
MW:
283.32
Mol File:
36417-86-4.mol
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N-p-trans-Coumaroyltyramine Chemical Properties

storage temp. 
2-8°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to light yellow
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N-p-trans-Coumaroyltyramine Usage And Synthesis

Chemical Properties

Soluble in methanol, ethanol, DMSO and other organic solvents, derived from the Solanaceae plant Solanum torvum.

Definition

ChEBI: Trans-N-p-coumaroyl tyramine is a hydroxycinnamic acid. It has a role as a metabolite.

Biological Activity

Np-trans-Coumaroyltyramine, a cinnamoylphenethyl amide isolated from Polygonum, acts as an acetylcholinesterase (AChE) inhibitor with IC50 of 122 μM. Np-trans-Coumaroyltyramine has anti-trypanosome activity with IC50 of 13.3 μM against T. brucei rhodesiense.

target

IC50: 122 μM (AChE)

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