5-Methoxyindole-3-acetonitrile Chemical Properties

Melting point:

65-69 °C (lit.)

Boiling point:

175-177 °C(Press: 0.01 Torr)

Density 

1.224±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

16.02±0.30(Predicted)

color 

Very Dark Brown

CAS DataBase Reference

2436-17-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2933998090

MSDS

• Language:English Provider:SigmaAldrich

5-Methoxyindole-3-acetonitrile Usage And Synthesis

Chemical Properties

Brown powder

Uses

5-Methoxyindole-3-acetonitrile is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors.

Uses

Reactant for preparation of (-)- and (+)-debromoflustramine B and its analogues as selective butyrylcholinesterase inhibitors
Reactant for preparation of carboline analogs as potent MAPKAP-K2 inhibitors
Reactant for preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment
Reactant for preparation of debromoflustramine B and labeled Me(3a)-13C-physostigmine
Reactant for preparation of physostigmine and physovenine
Reactant for preparation of phenethyl substituted indole derivatives as melatoninergic agonists and antagonists

5-Methoxyindole-3-acetonitrile(2436-17-1)Related Product Information

• (3-Methoxyphenyl)acetonitrile
• Anisole
• 5-Methoxy-3-indolecarboxylic acid
• 5-Methoxyindole
• p-Anisidine
• 1H-INDOL-3-OL
• 4-Methoxybenzyl cyanide
• 3-Indoleacetonitrile
• (Trifluoromethoxy)benzene
• 5-Methoxyoxindole
• 5-Methoxyindole-3-carboxaldehyde
• 5-Methoxy-2,3-dihydroindoline
• 5-Benzyloxyindole-3-acetonitrile
• acetonitrile
• 6-Methoxyindole-3-Acetonitrile97%,6-METHOXYINDOLE-3-ACETONITRILE
• 7-METHOXYINDOLE-3-ACETONITRILE
• TERT-BUTYL 3-(CYANOMETHYL)-5-METHOXY-1H-INDOLE-1-CARBOXYLATE
• (5-METHOXY-1-METHYL-1H-INDOL-3-YL)ACETONITRILE