3',5'-Dihydrodiol SiMvastatin (Mixture of DiastereoMers) Chemical Properties

Melting point:

65-85°C

Boiling point:

627.4±55.0 °C(Predicted)

Density 

1.19±0.1 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

13.50±0.40(Predicted)

color 

White to Off-White

Stability:

Hygroscopic

3',5'-Dihydrodiol SiMvastatin (Mixture of DiastereoMers) Usage And Synthesis

Chemical Properties

White Solid

Uses

(3S,5S)-Dihydroxy Simvastatin is a derivtive of Simvastatin (S485000). Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.

Uses

A metabolite of Simvastatin (S485000).

3',5'-Dihydrodiol SiMvastatin (Mixture of DiastereoMers)(159143-77-8)Related Product Information

• 3(R)-Hydroperoxy Simvastatin
• SiMvastatin Hydroxy Acid Ethyl Ester
• （3S)-Hydroxy Simvastatin
• 2’’-Desethyl-2’’-vinyl Simvastatin
• Simvastatin ammonium salt
• Lovastatin
• Simvastatin Impurity 10
• Epi Lovastatin
• SiMvastatin 4'-Methyl Ether
• 5'(S)-Hydroxy SiMvastatin DISCONTINUED
• 6-Oxo Simvastatin
• 2′-Ethyl Simvastatin
• SiMvastatin EP IMpurity G
• Simvastatin Dimer
• Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R,5S)-tetrahydro-4-hydroxy-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
• 6'-HYDROXY SIMVASTATIN
• 3(S)-Hydroperoxy Simvastatin
• Simvastatin Hydroxy Acid Methyl Ester