ChemicalBook > Product Catalog > Analytical Chemistry > Standard > Pharmaceutical Impurity Reference Standards > (2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane
(2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane
(2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane Basic information
- Product Name:
- (2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane
- Synonyms:
-
- (2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane
- tert-Butyl (thiazol-5-ylmethyl) ((2S,3S,5S)-3-hydroxy-1,6-diphenylhexane-2,5-diyl)dicarbamate
- N-[(1S,2S,4S)-4-[[(1,1-DiMethylethoxy)carbonyl]aMino]-2-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]carbaMic Acid 5-ThiazolylMethyl Ester
- Ritonavir Impurity 10(Ritonavir EP Impurity J)
- Ritonavir EP IMP J
- (2S, 3S, 5S)-5-(T-Butyloxycarbonylamino)-2- (N- ( (5-Thiazolyl)-Methoxycarbonyl) Amino)-1,6-Diphenhydroxyhexane
- Ritonavir EP Impurity J(BP Impurity J)
- ((Thiazol-5yl) methyl (2S,3S,5S)-5-(tertiary butoxy carbonyl) amino-3- hydroxy-1,6-diphenylhexan-2-yl carbamate)
- CAS:
- 162849-95-8
- MF:
- C28H35N3O5S
- MW:
- 525.66
- Mol File:
- 162849-95-8.mol
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(2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane Chemical Properties
- Melting point:
- 119-121°C
- Boiling point:
- 722.3±60.0 °C(Predicted)
- Density
- 1.219
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 11.48±0.46(Predicted)
- form
- Solid
- color
- White to Off-White
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(2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane Usage And Synthesis
Uses
N-[(1S,2S,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester (Ritonavir EP Impurity J) is an intermediate in the synthesis of Ritonavir (R535000), a selective HIV protease inhibitor used for the treatment of HIV infections and AIDS.
(2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexaneSupplier
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(2S,3S,5S)-5-(tert-Butoxycarbonylamino)-2-(N-5-thiazolylmethoxycarbonyl)amino-1,6-diphenyl-3-hydroxyhexane(162849-95-8)Related Product Information
- [5S-(5R*,8R*,10R*,11R*
- (4S,5S)-4-Benzyl-5-[(2S)-2-((4S)-4-isopropyl-2,5-dioxoiMidazolidin-1-yl)-3-phenylpropyl]-2-oxo-1,3-oxazolidine-3-carboxylate thiazol-5-ylMethyl Ester
- Ritonavir
- tert-Butyl rosuvastatin
- 3-AMINOMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER
- (S)-(-)-TERT-BUTYL TERT-BUTANETHIOSULFINATE
- tert-Butyl N-[2-hydroxy-1,1-bis(hydroxymethyl)-ethyl]carbamate
- Tert-butyl methanesulfonate
- DESTHIAZOLYLMETHYL RITONAVIR
- (5S,8S,9S,11S)-9-Hydr
- Ritonavir EP Impurity O
- N-[(1S,2S,4S)-4-(AcetylaMino)-2-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]carbaMic Acid 5-ThiazolylMethyl Ester
- Thiazol-5-ylmethyl ((2S,3S,5S)-5-((S)-2-amino-3-methylbutanamido)-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate
- 2,3-Dihydroxypropyl (3S,6S,8S,9S)-8-hydroxy-3-(1-methylethyl)-4,11-dioxo-6,9-bis(phenylmethyl)-13-(5-thiazolyl)-12-oxa-2,5,10-triazatridecanoate
- Hydroxy Ritonavir
- Ritonavir O-Acyl Isomer
- Ritonavir EP Impurity T
- (S)-2-(3-((2-Isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoic acid