Basic information Safety Supplier Related

Tofogliflozin

Basic information Safety Supplier Related

Tofogliflozin Basic information

Product Name:
Tofogliflozin
Synonyms:
  • Tofogliflozin(free)
  • CSG452;CSG-452
  • (3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol
  • Tofogliflozin
  • ((1S,3'R,4'S,5'S,6'R)-6-(4-ethylbenzyl)-3',4',5'-trihydroxy-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-6'-yl)methyl propionate
  • (1S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-6-(methoxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-3',4',5'-triol
  • (1S,3'R,4'S,5'S,6'R)-6-[(4-Ethylphenyl)Methyl]-3',4',5',6'-tetrahydro-6'-(hydroxyMethyl)spiro[isobenzofuran-1(3H),2'-[2H]pyran]-3',4',5'-triol
  • CSG 452
CAS:
903565-83-3
MF:
C22H26O6
MW:
386.44
Product Categories:
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
903565-83-3.mol
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Tofogliflozin Chemical Properties

Melting point:
75-79oC
Boiling point:
607.5±55.0 °C(Predicted)
Density 
1.38±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
13.06±0.70(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Tofogliflozin Usage And Synthesis

Uses

A novel, potent, and highly selective SGLT2 inhibitor that has been shown to improve glycemic control in diabetic mice and rats.

Definition

ChEBI: Tofogliflozin is a member of 2-benzofurans.

TofogliflozinSupplier

Chemsky (shanghai) International Co.,Ltd
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BOC Sciences
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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Tianjin SaiCheng Science and Technology Development Co., Ltd.
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Shanghai Synchem Pharma Co., ltd
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021-61984905-1 18016477331
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