N-Desethylamiodarone-D4 HCl Chemical Properties

Flash point:

9℃

storage temp. 

-20°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Light Brown

Major Application

clinical testing

InChI

1S/C23H25I2NO3.ClH/c1-3-5-9-20-21(16-8-6-7-10-19(16)29-20)22(27)15-13-17(24)23(18(25)14-15)28-12-11-26-4-2;/h6-8,10,13-14,26H,3-5,9,11-12H2,1-2H3;1H/i11D2,12D2;

InChIKey

OCQPMJVGWGJLLG-ZYMFQSNRSA-N

SMILES

Ic1c(c(cc(c1)C(=O)c2c3c([o]c2CCCC)cccc3)I)OC(C(NCC)([2H])[2H])([2H])[2H].Cl

Safety Information

Hazard Codes 

F,T

Risk Statements 

11-23/24/25-39/23/24/25

Safety Statements 

7-16-36/37-45

RIDADR 

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany 

1

Storage Class

3 - Flammable liquids

Hazard Classifications

Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1

N-Desethylamiodarone-D4 HCl Usage And Synthesis

Uses

A metabolite of Amiodarone, a non-selective ion channel blocker.

General Description

A Certified Spiking Solution^?and stable-labeled internal standard for use in therapeutic drug monitoring analyses by LC/MS. N-Desethylamiodarone is the primary, active metabolite of amiodarone, an antiarrhythmic agent marketed as Pacerone^?, Cordarone^?, Aratac, or Atlansil. N-Desethylamiodarone and amiodarone are monitored by clinical labs to ensure patients remain within the drug′s therapeutic range.

N-Desethylamiodarone-D4 HCl(1189960-80-2)Related Product Information

• 1-Methoxy AMiodarone
• 3-(4-HYDROXY-3-IODOBENZOYL)-2-BUTYLBENZOFURAN
• Amiodarone
• Amiodarone hydrochloride
• [[p-(2-methoxyethyl)phenoxy]methyl]oxirane
• Desethyl Amiodarone Hydrochloride
• Bis Des-iodo amiodarone HCl(Amiodarone impurity)
• (2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone
• Amiodarone Impurity 13
• 2-Butyl-3-(3,5-Diiodo-4-hydroxy benzoyl) benzofuran
• Di(N-desethyl) AMiodarone Hydrochloride
• 2-Butylbenzofuran
• 2-Diethylaminoethylchloride hydrochloride
• 2-Butyl-3-(4-hydroxybenzoyl)benzofuran
• Amiodarone-D4 HCl
• Dideiodo AMiodarone Hydrochloride
• Amiodarone Impurity 2
• Amiodarone N-oxide