H-THR-ARG-SER-ALA-TRP-NH2 Chemical Properties

Density 

1.53±0.1 g/cm3(Predicted)

storage temp. 

-15°C

pka

12.10±0.45(Predicted)

Sequence

Thr-Arg-Ser-Ala-Trp-NH2

H-THR-ARG-SER-ALA-TRP-NH2 Usage And Synthesis

Uses

Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroid hormone-related protein fragment that can inhibit bone resorption[1][2].

References

[1] Murrills RJ, et al. Lack of significant effect of carboxyl-terminal parathyroid hormone-related peptide fragments on isolated rat and chick osteoclasts. Calcif Tissue Int. 1995 Jul;57(1):47-51. DOI:10.1007/BF00298996
[2] Whitfield JF, et al. C-terminal fragments of parathyroid hormone-related protein, PTHrP-(107-111) and (107-139), and the N-terminal PTHrP-(1-40) fragment stimulate membrane-associated protein kinase C activity in rat spleen lymphocytes. J Cell Physiol. 1994 Mar;158(3):518-22. DOI:10.1002/jcp.1041580317

H-THR-ARG-SER-ALA-TRP-NH2(155918-12-0)Related Product Information

• RP107
• THR-ARG-SER-ALA-TRP
• H-THR-ARG-SER-ALA-TRP-NH2