DeMethoxycapillarisin Chemical Properties

Melting point:

>280 °C (decomp)

Boiling point:

535.9±50.0 °C(Predicted)

Density 

1.591±0.06 g/cm3(Predicted)

pka

6.39±0.40(Predicted)

DeMethoxycapillarisin Usage And Synthesis

Uses

Demethoxycapillarisin (6-Demethoxycapillarisin) inhibits PEPCK mRNA levels (IC50: 43 μM) by activation of the PI3K pathway. Demethoxycapillarisin decreases glucose production[1].

Definition

ChEBI: 6-Demethoxycapillarisin is a member of coumarins.

References

[1] Govorko D, et al. Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1503-10. DOI:10.1152/ajpendo.00420.2007

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