11-Hydroxy-sugiol
11-Hydroxy-sugiol Basic information
- Product Name:
- 11-Hydroxy-sugiol
- Synonyms:
-
- 11-Hydroxy-sugiol
- Demethylcryptojaponol
- 11-Hydroxylsugiol
- 12-O-deMethylcryptojapanol
- 11-hydroxy-sugio
- 11,12-dihydroxyabieta-8,11,13-trien-7-one
- 9(1H)-Phenanthrenone, 2,3,4,4a,10,10a-hexahydro-5,6-dihydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS,10aS)-
- CAS:
- 88664-08-8
- MF:
- C20H28O3
- MW:
- 316.43
- Product Categories:
-
- Diterpenoids
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 88664-08-8.mol
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11-Hydroxy-sugiol Chemical Properties
- Melting point:
- 192-194℃
- Boiling point:
- 482.2±45.0 °C(Predicted)
- Density
- 1.110±0.06 g/cm3 (20 ºC 760 Torr)
- pka
- 8.55±0.60(Predicted)
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11-Hydroxy-sugiol Usage And Synthesis
Definition
ChEBI: 11-hydroxysugiol is an abietane diterpenoid that is sugiol in which the hydrogen ortho to the phenolic hydroxy group has been replaced by a hydroxy group. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an EC 3.1.1.8 (cholinesterase) inhibitor and a plant metabolite. It is an abietane diterpenoid, a carbotricyclic compound, a meroterpenoid, a cyclic terpene ketone and a member of catechols. It is functionally related to a ferruginol and a sugiol.
Cytotoxicity
IC50 (μg/mL): 1.2 (A2780) (Topcu et al.2008)
11-Hydroxy-sugiolSupplier
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