ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Pyridine compound > Pyridine derivatives > 5,6-Dichloronicotinic acid
5,6-Dichloronicotinic acid
5,6-Dichloronicotinic acid Basic information
- Product Name:
- 5,6-Dichloronicotinic acid
- Synonyms:
-
- 5,6-DICHLORO-3-PYRIDINECARBOXYLIC ACID
- 5,6-DICHLORONICOTINIC ACID
- 5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID
- TIMTEC-BB SBB003623
- 5,6-Dichloropyridine-3-carboxylicacid,96%
- 5,6-Dichloro
- 5,6-DICHLORONICOTINIC ACID 98+%
- 5,6-Dichloronicotinic acid, 5,6-Dichloropyridine-3-carboxylic acid
- CAS:
- 41667-95-2
- MF:
- C6H3Cl2NO2
- MW:
- 192
- EINECS:
- 609-951-1
- Product Categories:
-
- Heterocycle-Pyridine series
- Chloropyridines
- Halopyridines
- Pyridine
- Building Blocks
- C5 to C6
- Pyridines, Pyrimidines, Purines and Pteredines
- pharmacetical
- Organic acids
- C6 to C7
- Chemical Synthesis
- Halogenated Heterocycles
- Heterocyclic Building Blocks
- Pyridines
- Intermediate
- Mol File:
- 41667-95-2.mol
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5,6-Dichloronicotinic acid Chemical Properties
- Melting point:
- 164-168 °C(lit.)
- Boiling point:
- 342.1±37.0 °C(Predicted)
- Density
- 1.612±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 2.87±0.10(Predicted)
- form
- Powder
- color
- White to beige to tan
- BRN
- 383740
- InChI
- InChI=1S/C6H3Cl2NO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H,10,11)
- InChIKey
- RNRLTTNKVLFZJS-UHFFFAOYSA-N
- SMILES
- C1=NC(Cl)=C(Cl)C=C1C(O)=O
- CAS DataBase Reference
- 41667-95-2(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-36-26
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29339900
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
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5,6-Dichloronicotinic acid Usage And Synthesis
Chemical Properties
white to off-white crystalline powder
Uses
5,6-Dichloronicotinic acid is a dihalonicotinic acid. It is used in the preparation of 5-chloro-6-iodonicotinic acid by iodine displacement.
Application
5,6-Dichloronicotinic acid is a compound that can be synthesized by reacting methyl ketones with chloroacetic acid. It is used in the synthesis of maleic anhydride and has been shown to inhibit the catalysis of acetylcholine chloride. It has also been shown to have an inhibitory effect on Alzheimer's disease. The kinetic mechanism for this inhibition occurs through the hydrolysis step of 5,6-Dichloronicotinic acid by magnesium chloride in hexane solution. The reactive acylation reaction proceeds when it reacts with acetic anhydride in the presence of pyridine.
5,6-Dichloronicotinic acid Preparation Products And Raw materials
Preparation Products
5,6-Dichloronicotinic acidSupplier
Shandong Xuanshuo Pharmaceutical Technology Co. LTD Gold
- Tel
- 15269103900
- suchangzhou@shiningpharm.com
Fuxin Crest Biotechnology Co. Ltd. Gold
- Tel
- 13062833949
- fred.wen@crcorporation.cn
Wuxi Kehua Biological Technology Co., Ltd. Gold
- Tel
- 0510-0510-86838766
- 2258830676@qq.com
ChengDu TongChuangYuan Pharmaceutical Co.Ltd Gold
- Tel
- 028-83379370 13880556291
- tcy@tcypharm.com
Jinan Dexinjia Bio&Tech Co., Ltd Gold
- Tel
- 0531-82375886 13001715031
- 3517280075@qq.com
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5,6-Dichloronicotinic acid(41667-95-2)Related Product Information
- Thionyl chloride
- Sodium dichloroisocyanurate
- Dichlorodimethylsilane
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- 6-Chloronicotinic acid
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- N,N-Dimethylacetamide
- 2,6-Dichloroisonicotinic acid
- Quinclorac
- 2,6-Dichloro-5-fluoronicotinic acid
- 4-Chloronicotinic acid
- EPA
- Dichloroethane
- 2-chloro-5-cyanopyridine
- 2-Mercaptonicotinic acid
- 6-Aminonicotinic acid
- 2,6-DICHLORONICOTINIC ACID 98%,2 6-DICHLORONICOTINIC ACID TECH. 90%,2,6-DICHLORONICOTINIC ACID
- 2,5-DICHLORONICOTINIC ACID