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5,6-Dichloronicotinic acid

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5,6-Dichloronicotinic acid Basic information

Product Name:
5,6-Dichloronicotinic acid
Synonyms:
  • 5,6-DICHLORO-3-PYRIDINECARBOXYLIC ACID
  • 5,6-DICHLORONICOTINIC ACID
  • 5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID
  • TIMTEC-BB SBB003623
  • 5,6-Dichloropyridine-3-carboxylicacid,96%
  • 5,6-Dichloro
  • 5,6-DICHLORONICOTINIC ACID 98+%
  • 5,6-Dichloronicotinic acid, 5,6-Dichloropyridine-3-carboxylic acid
CAS:
41667-95-2
MF:
C6H3Cl2NO2
MW:
192
EINECS:
609-951-1
Product Categories:
  • Heterocycle-Pyridine series
  • Chloropyridines
  • Halopyridines
  • Pyridine
  • Building Blocks
  • C5 to C6
  • Pyridines, Pyrimidines, Purines and Pteredines
  • pharmacetical
  • Organic acids
  • C6 to C7
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridines
  • Intermediate
Mol File:
41667-95-2.mol
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5,6-Dichloronicotinic acid Chemical Properties

Melting point:
164-168 °C(lit.)
Boiling point:
342.1±37.0 °C(Predicted)
Density 
1.612±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
2.87±0.10(Predicted)
form 
Powder
color 
White to beige to tan
BRN 
383740
InChIKey
RNRLTTNKVLFZJS-UHFFFAOYSA-N
CAS DataBase Reference
41667-95-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900

MSDS

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5,6-Dichloronicotinic acid Usage And Synthesis

Chemical Properties

white to off-white crystalline powder

Uses

5,6-Dichloronicotinic acid is a dihalonicotinic acid. It is used in the preparation of 5-chloro-6-iodonicotinic acid by iodine displacement.

Application

5,6-Dichloronicotinic acid is a compound that can be synthesized by reacting methyl ketones with chloroacetic acid. It is used in the synthesis of maleic anhydride and has been shown to inhibit the catalysis of acetylcholine chloride. It has also been shown to have an inhibitory effect on Alzheimer's disease. The kinetic mechanism for this inhibition occurs through the hydrolysis step of 5,6-Dichloronicotinic acid by magnesium chloride in hexane solution. The reactive acylation reaction proceeds when it reacts with acetic anhydride in the presence of pyridine.

5,6-Dichloronicotinic acid Preparation Products And Raw materials

Preparation Products

5,6-DICHLORONICOTINIC ACID ETHYL ESTER2,3-DICHLOROPYRIDINE-5-CARBONYL CHLORIDE

5,6-Dichloronicotinic acidSupplier

Shandong Xuanshuo Pharmaceutical Technology Co. LTD Gold
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ChengDu TongChuangYuan Pharmaceutical Co.Ltd Gold
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028-83379370 13880556291
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tcy@tcypharm.com
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