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2-Methyl-2-(4-vinylphenyl)propanoic acid

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2-Methyl-2-(4-vinylphenyl)propanoic acid Basic information

Product Name:
2-Methyl-2-(4-vinylphenyl)propanoic acid
Synonyms:
  • 2-Methyl-2-(4-vinylphenyl)propanoic acid
  • 2-Methyl-2-(4-vinylphenyl)propanoic acid-5
  • Alectinib Impurity 16
  • Benzeneacetic acid, 4-ethenyl-α,α-dimethyl-
CAS:
1256584-72-1
MF:
C12H14O2
MW:
190.24
Mol File:
1256584-72-1.mol
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2-Methyl-2-(4-vinylphenyl)propanoic acid Chemical Properties

Boiling point:
306.8±11.0 °C(Predicted)
Density 
1.076±0.06 g/cm3(Predicted)
pka
4.41±0.10(Predicted)
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Safety Information

HS Code 
2916399090
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2-Methyl-2-(4-vinylphenyl)propanoic acid Usage And Synthesis

Uses

2-?Methyl-?2-?(4-?vinylphenyl)?propanoic Acid is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.

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