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Dovitinib Dilactic acid (TKI258 Dilactic acid)

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Dovitinib Dilactic acid (TKI258 Dilactic acid) Basic information

Product Name:
Dovitinib Dilactic acid (TKI258 Dilactic acid)
Synonyms:
  • Dovitinib Dilactic acid (TKI258 Dilactic acid)
  • 2-Hydroxypropanoic acid compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
  • Dovitinib dilactic acid
  • TKI258 Dilactic acid
  • Propanoic acid, 2-hydroxy-, compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
  • Dovitinib dilactic acid, >=99%
  • Dovitinib (TKI-258) Dilactic Acid
  • CHIR-258 DILACTIC ACID
CAS:
852433-84-2
MF:
C24H27FN6O4
MW:
482.52
Product Categories:
  • Inhibitors
Mol File:
852433-84-2.mol
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Dovitinib Dilactic acid (TKI258 Dilactic acid) Chemical Properties

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO > 10 mM
form 
Powder
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Dovitinib Dilactic acid (TKI258 Dilactic acid) Usage And Synthesis

Uses

Dovitinib (TKI258, CHIR-258) is a multitargeted tyrosine kinase inhibitor of FLT3 and c-KIT with IC50 of 1 nM and 2 nM, respectively.

Uses

Dovitinib Dilactic acid is the Dilactic acid of Dovitinib (D537000, Lactate salt), which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit), also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Potent FGFR inhibitor

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