gyMneMic acid I
gyMneMic acid I Basic information
- Product Name:
- gyMneMic acid I
- Synonyms:
-
- gyMneMic acid I
- GYMNEMIC ACID I,98%
- Gymnema Extract (Standard)
- b-D-Glucopyranosiduronic acid, (3b,4a,16b,21b,22a)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl
- β-D-Glucopyranosiduronic acid, (3β,4α,16β,21β,22α)-28-(acetyloxy)-16,22,23-trihydroxy-21-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl
- (2S,3S,4S,5R,6R)-6-[[(3S,4R,4aR,6aR,6bS,8S,8aR,9R,10R,12aS,14aR,14bR)-8a-(acetyloxymethyl)-8,9-dihydroxy-4-(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(E)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,4,5
- gyMneMic acid I USP/EP/BP
- (+)-Gymnemic Acid I
- CAS:
- 122168-40-5
- MF:
- C43H66O14
- MW:
- 806.98
- Mol File:
- 122168-40-5.mol
gyMneMic acid I Chemical Properties
- Boiling point:
- 872.1±65.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble
- form
- A crystalline solid
- pka
- 2.82±0.70(Predicted)
- color
- White to light yellow
- LogP
- 5.979 (est)
gyMneMic acid I Usage And Synthesis
Description
Gymnemic acid I is a triterpene glycoside that has been found in G. sylvestre and has antihyperglycemic activities. It inhibits glucose-induced phosphorylation of serine 70 on S6 kinase (S6K1) and serine 2448 on mTOR, caspase-3 activity, and apoptosis, as well as increases autophagy in MIN-6 pancreatic β cells when used at a concentration of 5 μg/ml. Gymnemic acid I has been used as a reference compound to compare the potency of plant-derived sweet taste inhibitors.
Uses
(+)-Gymnemic Acid I is one of the components extracted from the leaves of Gymnema sylvestre, known for inhibitory acitivity against glucose absorption. However, (+)-Gymnemic Acid I lacks this activity, unlike other forms of gymnemic acids.
Definition
ChEBI: Gymnemic acid I is a triterpenoid saponin.
gyMneMic acid ISupplier
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gyMneMic acid I(122168-40-5)Related Product Information
- 7β-Hydroxylathyrol
- Carboxyatractyloside
- Pachymic acid
- Olean-12-ene-3β,16β,21β,23,28-pentol
- roburic acid
- Terrestrosin K
- (3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate]
- Poricoic acid A(F)
- ALLEOSIDE A
- Madecassic acid
- Madecassoside
- Gymnemagenin
- dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate
- Terrestrosin D
- BITTER MELON P.E.
- beta-Sitosterol
- Protocatechualdehyde
- N/A