Basic information Safety Supplier Related

Loxoprofen Ring-opening IMpurity

Basic information Safety Supplier Related

Loxoprofen Ring-opening IMpurity Basic information

Product Name:
Loxoprofen Ring-opening IMpurity
Synonyms:
  • Loxoprofen Ring-opening IMpurity
  • Loxoprofen Impurity K
  • Loxoprofen Impurity 12
  • Bendamustine Impurity: 6-[4-(1-Carboxy-ethyl)-phenyl]-5-oxo-hexanoic acid
  • 4-(1-Carboxyethyl)-δ-oxo-benzenehexanoic Acid
  • Benzenehexanoic acid, 4-(1-carboxyethyl)-δ-oxo-
  • Loxoprofen sodium degrades impurity B
  • 4-(1-Carboxyethyl)-d-oxo-benzenehexanoic Acid
CAS:
1091621-61-2
MF:
C15H18O5
MW:
278.3
Mol File:
1091621-61-2.mol
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Loxoprofen Ring-opening IMpurity Chemical Properties

Boiling point:
504.8±35.0 °C(Predicted)
Density 
1.238±0.06 g/cm3(Predicted)
pka
4.32±0.10(Predicted)
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Loxoprofen Ring-opening IMpurity Usage And Synthesis

Uses

4-(1-Carboxyethyl)-δ-oxo-benzenehexanoic Acid is a degradation product of Loxoprofen (L472900, Na salt), a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. It becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.

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