Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid)
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid) Basic information
- Product Name:
- Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid)
- Synonyms:
-
- Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid)
- 2-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-methylphenyl isobutyrate mandelate
- Fesoterodine L-mandelate
- Fesoterodine L mandelate,Fesoterodine Lmandelate
- CAS:
- 1206695-46-6
- MF:
- C34H45NO6
- MW:
- 563.74
- Mol File:
- 1206695-46-6.mol
More
Less
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid) Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
More
Less
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid) Usage And Synthesis
Uses
Fesoterodine ((S)-2-Hydroxy-2-phenylacetic Acid) is a salt of Fesoterodine, an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
in vivo
Fesoterodine L-mandelate (0.01-1 mg/kg; IV) reduces the micturition pressure and increases bladder capacity and ICIs (intercontraction intervas) at the lowest dose tested of 0.01 mg/kg[3].
| Animal Model: | Bladders from female Sprague-Dawley rats (225-275 g)[3] |
| Dosage: | 0.01, 0.1 and 1 mg/kg |
| Administration: | IV |
| Result: | Reduced the micturition pressure and increased bladder capacity and ICIs at the lowest dose tested of 0.01 mg/kg. |
IC 50
mAChR1; mAChR3; mAChR4; mAChR5
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid)Supplier
ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel
- 18149758185 18149758185;
- sales-cpd@caerulumpharma.com
AbaChemScene
- Tel
- 732-484-9848
- sales@chemscene.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
Hahui (Shanghai) Pharmaceutical Technology Co., Ltd.
- Tel
- 021-13472633-721 13472633721
- 454407203@qq.com
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
- Tel
- 18818260767
- sales@chemegen.com
More
Less
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid)(1206695-46-6)Related Product Information
- Fesoterodine Diol Dimer Monoester
- Fesoterodine Impurity 8
- (S)-(+)-O-Acetyl-L-mandelic acid
- Deoxy Fesoterodine
- 3-(3-Aminopropyl)benzoic Acid Hydrochloride
- (R)-5-HydroxyMethyl Tolterodine ForMate
- Fesoterodine Diol Dimer
- (R)-5-HydroxyMethyl Tolterodine
- Benzenepropanol, 2-hydroxy-5-(hydroxyMethyl)-γ-phenyl-
- Fesoterodine Related Impurity 2
- (S)-Fesoterodine HCl
- Phenol, 2-[3-[bis(1-Methylethyl)aMino]-1-phenylpropyl]-4-(MethoxyMethyl)-
- Fesoterodine Impurity 5
- ICOFQCJKJOISKD-HSZRJFAPSA-N
- rac 5-Hydroxymethyl Tolterodine, 90% by HPLC
- Fesoterodinefumarate
- Fesoterodine Impurity 6
- O-Isobutyryl (R)-Fesoterodine