MPEG8-N3 Chemical Properties

refractive index 

1.4590 to 1.4630

storage temp. 

Store at Room Tem.

form 

clear liquid

color 

Colorless to Light yellow to Light orange

Safety Information

HS Code 

2929.90.5090

MPEG8-N3 Usage And Synthesis

Description

m-PEG8-azide is a monodisperse PEG linker containing an azide group. It isreactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Uses

m-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74

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