2-Methyl-1,3-cyclopentanedione Chemical Properties

Melting point:

212-215 °C (lit.)

Boiling point:

213°C (estimate)

Density 

1.0795 (rough estimate)

refractive index 

1.4550 (estimate)

storage temp. 

Store below +30°C.

solubility 

Solubility in hot Methanol (almost transparency).

pka

10.83±0.20(Predicted)

form 

Crystalline Powder

color 

Light beige to tan

PH

2.95 at 24.7℃ and 10g/L

BRN 

1237255

InChIKey

HXZILEQYFQYQCE-UHFFFAOYSA-N

LogP

-0.8 at 30℃ and pH7.66

CAS DataBase Reference

765-69-5(CAS DataBase Reference)

NIST Chemistry Reference

1,3-Cyclopentanedione, 2-methyl-(765-69-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-36-26

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29142900

MSDS

• Language:English Provider:2-Methylcyclopentane-1,3-dione
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Methyl-1,3-cyclopentanedione Usage And Synthesis

Chemical Properties

LIGHT BEIGE TO TAN CRYSTALLINE POWDER

Uses

2-Methyl-1,3-cyclopentanedione was used as a reactant in the identification and characterization of benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

Uses

2-Methyl-1,3-cyclopentanedione hs been used to explore deoxycholic acid (DCA) induced changes in cell signaling. DCA is a secondary bile acid implicated in numerous pathological conditions. It has also been used in the synthesis of (-)-curcumanolide A and (-)-curcumalactone by aldol-lactonization.

Synthesis Reference(s)

Synthetic Communications, 19, p. 373, 1989 DOI: 10.1080/00397918908050676

2-Methyl-1,3-cyclopentanedione(765-69-5)Related Product Information

• Kresoxim-methyl
• Methanol
• Methylcyclohexane
• Methyl salicylate
• Basic Violet 1
• Octamethylcyclotetrasiloxane
• Tribenuron methyl
• METSULFURON METHYL
• Hexamethylcyclotrisiloxane
• Cyclopropyl methyl ketone
• Acetylacetone
• 1,3-Cyclopentanedione
• 1,1,3,3,5,5-hexamethyl-1,3,5-trisilacyclohexane
• Octamethylcyclotetrasilazane
• 1,3-Cyclopentadiene
• Methylparaben
• METHYLCYCLOPENTADIENE DIMER
• Methyl acrylate