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IsoliMonexic acid

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IsoliMonexic acid Basic information

Product Name:
IsoliMonexic acid
Synonyms:
  • IsoliMonexic acid
  • Limonexylic acid
  • Rutaevinexic acid
  • (17R,23Xi)-1alpha,4
  • 14,15beta-Diepoxy-17,19,23,23-tetrahydroxy-4,4,8-trimethyl-7-oxo-3,4
  • 16,17-diseco-24-nor-5alpha,13alpha,14beta-chol-20(22)-en-3,16,21-trisaeure-3=>19
  • Isolimonexin
  • 21=>23-trilacton
CAS:
73904-93-5
MF:
C26H30O10
MW:
502.52
Mol File:
73904-93-5.mol
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IsoliMonexic acid Chemical Properties

Melting point:
315-316℃
Boiling point:
788.3±60.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
pka
9.79±0.40(Predicted)
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IsoliMonexic acid Usage And Synthesis

Uses

Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and anti-aromatase (IC50=25.60 μM) properties[1].

IC 50

Aromatase

References

[1] Jinhee Kim, et al. Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells. Food Funct. 2013 Feb;4(2):258-65. DOI:10.1039/c2fo30209h
[2] Jaiprakash R Patil, et al.Bioactive compounds from Mexican lime ( Citrus aurantifolia ) juice induce apoptosis in human pancreatic cells. J Agric Food Chem. 2009 Nov 25;57(22):10933-42. DOI:10.1021/jf901718u

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