Basic information Safety Supplier Related

THAPSIGARGICIN

Basic information Safety Supplier Related

THAPSIGARGICIN Basic information

Product Name:
THAPSIGARGICIN
Synonyms:
  • THAPSIGARGICIN
  • Hexanoic acid, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl ester
CAS:
67526-94-7
MF:
C32H46O12
MW:
622.7
Product Categories:
  • Intracellular Calcium Regulators
  • Cell Signaling and Neuroscience
  • Intracellular Calcium Signaling
Mol File:
67526-94-7.mol
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THAPSIGARGICIN Chemical Properties

storage temp. 
−20°C
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Safety Information

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
26-36
WGK Germany 
3

MSDS

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THAPSIGARGICIN Usage And Synthesis

Uses

Thapsigargicin (Thapsigargicine) is a activator of mast cells and leukocytes. Thapsigargicin induces histamine release from rat peritoneal mast cells and human basophil leukocytes. Thapsigargicin increases the cytoplasmic free calcium level in intact human blood platelets[1].

References

[1] Ali H, et al. The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response. Br J Pharmacol. 1985 Jul;85(3):705-12. DOI:10.1111/j.1476-5381.1985.tb10567.x

THAPSIGARGICINSupplier

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