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Idarubicin

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Idarubicin Basic information

Product Name:
Idarubicin
Synonyms:
  • 11-trihydroxy-(7s-cis)-alpha-l-lyxo-hexopyranosyl)oxy)-
  • 4-demethoxy-daunomyci
  • 4-demethoxydaunomycin
  • 4-demethoxydaunorubicin
  • 4-Demethoxy-daunorubicin
  • 7,8,9,10-tetrahydro-9-acetyl-7-((3-amino-2,3,6-trideoxy-12-naphthacenedione
  • nsc-256439
  • (7S)-9-Acetyl-7β-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9β,11-trihydroxy-5,12-naphthacenedione
CAS:
58957-92-9
MF:
C26H27NO9
MW:
497.49
EINECS:
1806241-263-5
Product Categories:
  • Active Pharmaceutical Ingredients
Mol File:
58957-92-9.mol
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Idarubicin Chemical Properties

Boiling point:
589.46°C (rough estimate)
Density 
1.3477 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
form 
solid
pka
pKa 4.73± 0.21 (Uncertain)
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Safety Information

Hazard Codes 
T+
Risk Statements 
60-61-28-40
Safety Statements 
53-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
HB7877000

MSDS

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Idarubicin Usage And Synthesis

Uses

Antineoplastic.

Indications

Idarubicin (Idamycin) differs from its parent compound, daunorubicin, by the absence of the methoxy group in the anthracycline ring structure. Its mechanisms of action and resistance are similar to those of doxorubicin and daunorubicin; however, it is more lipophilic and more potent than these other anthracyclines. Idarubicin undergoes extensive hepatic metabolism and biliary excretion. Adverse reactions of idarubicin are similar to those of its congeners.

Definition

ChEBI: Idarubicin is a monosaccharide derivative, an anthracycline antibiotic and a deoxy hexoside. It derives from a hydride of a tetracene.

Idarubicin Preparation Products And Raw materials

Raw materials

DichloromethaneAcetic acid glacialMagnesium sulfate1,4-DioxaneArgonDOWEX(R) 50WX4 HYDROGEN FORM

IdarubicinSupplier

BeiJing Hwrk Chemicals Limted
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LGM Pharma
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1-(800)-881-8210
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Beijing HuaMeiHuLiBiological Chemical
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010-56205725
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NCE Biomedical Co.,Ltd.
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4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Synchem OHG
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+49 5662 408730
Email
info@synchem.de
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