Ethyl (triphenylphosphoranylidene)acetate Chemical Properties

Melting point:

128-130 °C (lit.)

Boiling point:

490.4±28.0 °C(Predicted)

Density 

1.086 g/cm3

storage temp. 

2-8°C

solubility 

Chloroform, THF

form 

Powder

color 

White to light yellow

Water Solubility 

Insoluble

Sensitive 

Air Sensitive

BRN 

754639

InChIKey

IIHPVYJPDKJYOU-UHFFFAOYSA-N

CAS DataBase Reference

1099-45-2(CAS DataBase Reference)

EPA Substance Registry System

Acetic acid, (triphenylphosphoranylidene)-, ethyl ester (1099-45-2)

Safety Information

Hazard Codes 

T,Xi,Xn

Risk Statements 

36/37/38-25-20/21/22

Safety Statements 

22-24/25-45-37/39-26-36

RIDADR 

UN2811

WGK Germany 

3

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29310095

MSDS

• Language:English Provider:(Carbethoxymethylene)triphenylphosphorane
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Ethyl (triphenylphosphoranylidene)acetate Usage And Synthesis

Description

Ethyl (triphenylphosphoranylidene)acetate is a common Wittig reagent in organic synthesis as well as a cholinesterase inhibitor that inhibits both AChE and BChE. It is used in the preparation of indole from o-nitrobenzaldehydes, coumarins from o-hydroxy acetophenone.

Chemical Properties

Off-White Solid

Uses

A common Wittig reagent. A cholinesterase inhibitor.

Uses

(Ethoxycarbonylmethylene)triphenylphosphoran is used as a Wittig reagent in organic synthesis. It is used in the preparation of indole from o-nitrobenzaldehydes, coumarins from o-hydroxy acetophenone. It acts as an inhibitor and inhibits the activity of cholinesterase.

Purification Methods

Crystallise it by dissolving it in AcOH and adding pet ether (b 40-50o) to give colourless plates. UV (A 1% ): 222nm (865) and 268nm (116) [Isler et max 1mm al. Helv Chim Acta 40 1242 1957]. [Beilstein 16 IV 977.]

Ethyl (triphenylphosphoranylidene)acetate(1099-45-2)Related Product Information

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