EPO Chemical Properties

storage temp. 

−20°C

form 

lyophilized powder

Cosmetics Ingredients Functions

SKIN PROTECTING

Safety Information

WGK Germany 

3

RTECS 

KF5885000

F 

10-21

MSDS

• Language:English Provider:SigmaAldrich

EPO Usage And Synthesis

Description

Recombinant erythropoietin (EPO) is currently indicated for use only in anemia associated with renal transplant or end-stage renal disease. Widened indications for use in other forms of anemia, accompanied by price reductions as a result of keen competition, have been projected for EPO in the future.

Originator

Amgen (USA)

brand name

Eprex

Description

EPO Mouse Recombinant produced in Baculovirus is a single glycosylated polypeptide chain containing 176 amino acids (27-192 aa) and having a molecular mass of 19.8kDa.
EPO is fused to a 9 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells

Background

Erythropoietin or EPO is a hormone (glycoprotein), part of the type I cytokine group of proteins. EPO is found mainly in the kidney tissue, produced from fibroblast-like cortical interstitial cells near the proximal tubules. EPO is also present in the blood, where it acts as red cell production regulator, by the promotion of differentiation of erythroid and thereby starts hemoglobin synthesis. Furthermore, EPO has neuroprotective activity towards brain injuries & anti-apoptotic activity in different tissues.

EPO()Related Product Information

• Bovine FGF
• Erythropoietin