4-Fluorophenylacetylene Chemical Properties

Melting point:

26-27 °C(lit.)

Boiling point:

55-56 °C40 mm Hg(lit.)

Density 

1.048 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.516(lit.)

Flash point:

29 °C

storage temp. 

2-8°C

solubility 

soluble in Chloroform, Diethyl Ether, Ethanol

form 

Liquid After Melting

Specific Gravity

1.048

color 

Clear colorless to yellow

Water Solubility 

Soluble in chloroform, diethyl ether, acetone, dichloromethane, hexane and ethanol. Highly soluble in toluene. Insoluble in water.

BRN 

1099285

InChIKey

QXSWHQGIEKUBAS-UHFFFAOYSA-N

CAS DataBase Reference

766-98-3(CAS DataBase Reference)

NIST Chemistry Reference

4-FC6H4CCH(766-98-3)

Safety Information

Hazard Codes 

F,Xi

Risk Statements 

36/37/38-11-10

Safety Statements 

16-26-36-37/39

RIDADR 

UN 1325 4.1/PG 2

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

4.1

PackingGroup 

II

HS Code 

29039990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

4-Fluorophenylacetylene Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

Intermediates of liquid Crystals. As pharmaceutical intermediates. As organic synthesis intermediates. For vacuum deposition.

Uses

1-Ethynyl-4-fluorobenzene, a substituted phenylacetylene, may be used in the synthesis of aryl acetylenes, via Sonogashira type cross coupling reaction with various haloarenes in the presence of bis(μ-iodo)bis((-)-sparteine)dicopper(I) catalyst.

Uses

Intermediates of Liquid Crystals

Synthesis Reference(s)

Synthesis, p. 589, 1996 DOI: 10.1055/s-1996-4265

General Description

1-Ethynyl-4-fluorobenzene (pFAB) is a fluorobenzene derivative. Trianionic pincer alkylidyne complex catalyzed polymerization of 1-ethynyl-4-fluorobenzene has been reported. The surface of the iodophenyl-terminated organic monolayers has been modified by Sonogashira coupling of the iodophenyl groups found on the surface with pFAB. Dimerization catalyzed by Y[N(TMS)₂]₃ and 4-chloroaniline gave exclusive formation of one of three possible enediynes in excellent yield.

4-Fluorophenylacetylene(766-98-3)Related Product Information

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