2-FLUORO-5-FORMYLBENZONITRILE Chemical Properties

Melting point:

80-84 °C (lit.)

Boiling point:

215.6±20.0 °C(Predicted)

Density 

1.25±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform, Methanol

form 

Solid

color 

White

InChI

InChI=1S/C8H4FNO/c9-8-2-1-6(5-11)3-7(8)4-10/h1-3,5H

InChIKey

MOFRJTLODZILCR-UHFFFAOYSA-N

SMILES

C(#N)C1=CC(C=O)=CC=C1F

CAS DataBase Reference

218301-22-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard Note 

Harmful

HazardClass 

IRRITANT

HS Code 

29269090

MSDS

• Language:English Provider:SigmaAldrich

2-FLUORO-5-FORMYLBENZONITRILE Usage And Synthesis

Description

2-Fluoro-5-formylbenzonitrile is a pharmaceutical intermediate compound used in the preparation of Olaparib, a PARP inhibitor for the treatment of a variety of cancers including advanced ovarian, fallopian tube, or primary peritoneal cancers with a certain hereditary (germline) or acquired (somatic) abnormality of the BRCA gene.

Chemical Properties

White Solid

Uses

2-Fluoro-5-formylbenzonitrile may be used in the synthesis of 3-cyano-4-fluorobenzyl bromide.

Uses

2-Fluoro-5-ForMyl-benzonitrile is used in the preparation of heterocyclic compounds as PARP inhibitors for medical use.

General Description

2-Fluoro-5-formylbenzonitrile is a benzonitrile derivative.

2-FLUORO-5-FORMYLBENZONITRILE(218301-22-5)Related Product Information

• 3,4-Difluorobenzonitrile
• 2,6-Difluorobenzonitrile
• 2,4-Difluorobenzonitrile
• o-Phthalaldehyde
• Olaparib
• 4-Fluorocinnamaldehyde
• 3-Cyanobenzaldehyde
• 4-Fluorobenzaldehyde
• 4-CHLORO-3-FORMYL-BENZONITRILE
• 3-FLUORO-5-FORMYLBENZONITRILE
• 6-(DIMETHYLAMINO)-2-FLUORO-3-FORMYLBENZONITRILE,6-(Dimethylamino)-2-fluoro-3-formylbenzonitrile, 95+%