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Cefteram pivoxil

Basic information Safety Supplier Related

Cefteram pivoxil Basic information

Product Name:
Cefteram pivoxil
Synonyms:
  • 2,2-Dimethylpropanoyloxymethyl (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetylamino]-3-(5-methyl-2H-tetrazol-2-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • CEFTERAM
  • Cefteram pivoxil
  • (+)-(6R,7R)-7-[(Z)-2-(2-Amincr4-thiazolyl)-2-(methoxyimino)acetami-do]-3-[(5-methyl-2H-tetrazol-2-y1)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Ceftetrame
  • Ro-19-5247
  • T-2525
  • Tomimn
CAS:
82547-58-8
MF:
C16H17N9O5S2
MW:
479.49
Product Categories:
  • Amines
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
Mol File:
82547-58-8.mol
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Cefteram pivoxil Chemical Properties

Melting point:
>175°C (dec.)
Density 
1.95±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
2.62±0.50(Predicted)
color 
White to Pale Yellow
InChI
InChI=1S/C16H17N9O5S2/c1-6-20-23-24(21-6)3-7-4-31-14-10(13(27)25(14)11(7)15(28)29)19-12(26)9(22-30-2)8-5-32-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29)/b22-9-/t10-,14-/m1/s1
InChIKey
XSPUSVIQHBDITA-RKYNPMAHSA-N
SMILES
N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\OC)=O)C1=O)SCC(CN1N=NC(C)=N1)=C2C(O)=O
CAS DataBase Reference
82547-58-8(CAS DataBase Reference)
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Cefteram pivoxil Usage And Synthesis

Description

Cefteram pivoxil is an orally-active cephalosponn antibiotic with a broad spectrum of activity. It is reportedly effective against Cirrobacrer, indole-positive Proreus and Enrerobacrer species resistant to cefaclor, cephalexin and amoxicillin. Cefteram pivoxil is indicated primarily for urinary tract infections.

Chemical Properties

Pale Yellow Solid

Originator

Toyama (Japan)

Uses

Orally active cephalosporin antibiotic, antibacterial.

Definition

ChEBI: Cefteram is a cephalosporin compound having (5-methyl-2H-tetrazol-2-yl)methyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups; a third-generation cephalosporin antibiotic.

brand name

Tomiron

Antimicrobial activity

A semisynthetic cephalosporin formulated for oral administration as the prodrug ester, cefteram pivoxil. Activity is similar to that of cefixime, but with slightly better activity against staphylococci and some Gram-negative rods.
Available in Japan.

Cefteram pivoxil Preparation Products And Raw materials

Raw materials

Cefteram pivoxilSupplier

Qilu Antibiotics Pharmaceutical Co., Ltd. Gold
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0531-83128558
Shenzhen Excellent Biomedical Technology Co., Ltd. Gold
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18318671572
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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jkinfo@jkchemical.com
LGM Pharma
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1-(800)-881-8210
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inquiries@lgmpharma.com
Chemsky(shanghai)International Co.,Ltd.
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021-50135380
Email
shchemsky@sina.com