Cefteram pivoxil Chemical Properties

Melting point:

>175°C (dec.)

Density 

1.95±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

DMF (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

2.62±0.50(Predicted)

color 

White to Pale Yellow

InChI

InChI=1S/C16H17N9O5S2/c1-6-20-23-24(21-6)3-7-4-31-14-10(13(27)25(14)11(7)15(28)29)19-12(26)9(22-30-2)8-5-32-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29)/b22-9-/t10-,14-/m1/s1

InChIKey

XSPUSVIQHBDITA-RKYNPMAHSA-N

SMILES

N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\OC)=O)C1=O)SCC(CN1N=NC(C)=N1)=C2C(O)=O

CAS DataBase Reference

82547-58-8(CAS DataBase Reference)

Cefteram pivoxil Usage And Synthesis

Description

Cefteram pivoxil is an orally-active cephalosponn antibiotic with a broad spectrum of activity. It is reportedly effective against Cirrobacrer, indole-positive Proreus and Enrerobacrer species resistant to cefaclor, cephalexin and amoxicillin. Cefteram pivoxil is indicated primarily for urinary tract infections.

Chemical Properties

Pale Yellow Solid

Originator

Toyama (Japan)

Uses

Orally active cephalosporin antibiotic, antibacterial.

Definition

ChEBI: Cefteram is a cephalosporin compound having (5-methyl-2H-tetrazol-2-yl)methyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups; a third-generation cephalosporin antibiotic.

brand name

Tomiron

Antimicrobial activity

A semisynthetic cephalosporin formulated for oral administration as the prodrug ester, cefteram pivoxil. Activity is similar to that of cefixime, but with slightly better activity against staphylococci and some Gram-negative rods.
Available in Japan.

Cefteram pivoxil(82547-58-8)Related Product Information

• 4'-Methoxyacetophenone
• Methyl 3-oxovalerate
• Cefditoren pivoxil
• p-Anisaldehyde
• Methyl isobutyrylacetate
• 3-Methoxybenzaldehyde
• 4-Methoxybenzoic acid
• Anisole
• 4-Methoxybenzylchloride
• p-Anisidine
• Methyl benzoylformate
• (Trifluoromethoxy)benzene
• Cefteram pivoxil
• Ceftizoxime
• Cefetamet hydrochloride
• 2-(2-AMINOTHIAZOL-4-YL)ETHYLAMINE
• 2-(2-AMINO-THIAZOL-4-YL)-ACETAMIDE
• 4-Thiazoleacetamide