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1,1-Di-tert-butoxytrimethylamine

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1,1-Di-tert-butoxytrimethylamine Basic information

Product Name:
1,1-Di-tert-butoxytrimethylamine
Synonyms:
  • N,N-DIMETHYLFORMAMIDE DI-TERT-BUTYL ACET AL, DERIVATIZATION GRADE
  • 1,1-Di-tert-butoxytrimethylamine, 1,1-Di-tert-butoxy-N,N-dimethylmethylamine
  • N,N-Dimethyl-1,1-bis[(2-methylpropan-2-yl)oxy]methanamine
  • Di-tert-butoxy(dimethylamino)methane
  • N,N-Dimethyldi(tert-butyloxy)methanamine
  • N,N-Dimethyldi-tert-butoxymethanamine
  • N,N-Dimethylformamide di-tert-butyl acetal, tech. 90%
  • N,N-Dimethylformamide Di-tert-butyl Acetal [for Esterification]
CAS:
36805-97-7
MF:
C11H25NO2
MW:
203.32
EINECS:
253-222-7
Product Categories:
  • Analytical Chemistry
  • Esterification & Alkylation (GC Derivatizing Reagents)
  • GC Derivatizing Reagents
  • N,N-Dimethylformamide Dialkylacetals (GC Derivatizing Reagents)
Mol File:
36805-97-7.mol
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1,1-Di-tert-butoxytrimethylamine Chemical Properties

Boiling point:
56-57 °C8 mm Hg(lit.)
Density 
0.848 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.413(lit.)
Flash point:
93 °F
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Miscible with toluene and benzene.
form 
clear liquid
pka
5.34±0.50(Predicted)
color 
Colorless to Almost colorless
Specific Gravity
0.848
Sensitive 
Moisture Sensitive
BRN 
969629
InChIKey
DBNQIOANXZVWIP-UHFFFAOYSA-N
CAS DataBase Reference
36805-97-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
10-36/37/38
Safety Statements 
26-36
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
10-21
HazardClass 
3
PackingGroup 
III
HS Code 
29221990

MSDS

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1,1-Di-tert-butoxytrimethylamine Usage And Synthesis

Uses

Reagent used for the preparation of indolizines via intermolecular cyclization of picolinium salts.

Uses

N,N-Dimethylformamide di-tert-butyl acetal may be used in the synthesis of following:

  • (S)-2-(1-tert-butoxycarbonyl-2-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}ethylamino)benzoic acid methyl ester
  • 3-O-tert-butylmorphine
  • tert-butylesters of pyrrole- and indolecarboxylic acids

Synthesis Reference(s)

Synthetic Communications, 15, p. 723, 1985 DOI: 10.1080/00397918508063864

General Description

N,N-Dimethylformamide di-tert-butyl acetal is an derivatizing reagent.

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