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Fmoc-D-Tyr(tBu)-OH

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Fmoc-D-Tyr(tBu)-OH Basic information

Product Name:
Fmoc-D-Tyr(tBu)-OH
Synonyms:
  • FMOC-O-T-BUTYL-D-TYROSINE
  • FMOC-O-TERT-BUTYL-D-TYROSINE
  • FMOC-D-TYR(TBU)-OH 99%
  • N-α-Fmoc-O-tert-butyl-D-tyrosine
  • NALPHA-9-Fluorenylmethoxycarbonyl-O-tert-butyl-D-tyrosine
  • 9-fluorenylmethyloxycarbonyl-D-tyrosine(tert-butyl)-OH
  • (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-tert-butoxyphenyl)propanoic acid
  • Fmoc-D-Tyr(tBu)-OH (Fmoc-O-tert-butyl-D-tyrosine)
CAS:
118488-18-9
MF:
C28H29NO5
MW:
459.53
Product Categories:
  • Amino Acids
  • Tyrosine [Tyr, Y]
  • Fmoc-Amino Acids and Derivatives
  • Fmoc-Amino acid series
Mol File:
118488-18-9.mol
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Fmoc-D-Tyr(tBu)-OH Chemical Properties

Melting point:
150.0 to 154.0 °C
Boiling point:
658.2±55.0 °C(Predicted)
Density 
1.218±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
2.97±0.10(Predicted)
form 
powder to crystal
color 
White to Almost white
Water Solubility 
Soluble in 1 mmole in 2 ml dimethylformamide (Clearly soluble). Slightly soluble in water.
BRN 
6691868
InChIKey
JAUKCFULLJFBFN-RUZDIDTESA-N
SMILES
C(O)(=O)[C@@H](CC1=CC=C(OC(C)(C)C)C=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference
118488-18-9(CAS DataBase Reference)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
10
HS Code 
29224999

MSDS

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Fmoc-D-Tyr(tBu)-OH Usage And Synthesis

Description

Fmoc-D-Tyr(tBu)-OH is a precursor for the synthesis of thyroxine, dopa and adrenaline in medicine. It is directly involved in the synthesis of neurotransmitters such as dopamine, norepinephrine and epinephrine, and in the control of neurotransmitter levels, and is involved in the synthesis of hormones of thyroid, pituitary and other glands. In the feed industry, Fmoc-D-Tyr(tBu)-OH can be used as a feed additive in the feed of chicks. On the one hand, it minimizes the amount of phenylalanine converted to tyrosine to maintain the balance of amino acids in the growth of livestock and poultry. On the other hand, it can avoid chicks and piglets to lose weight due to insufficient tyrosine in the body and the destruction of thyroid and adrenal hormones.

Chemical Properties

White powder

Uses

N-Fmoc-O-tert-butyl-D-tyrosine is potentially useful for proteomics studies and solid phase peptide synthesis techniques.

Definition

Fmoc-D-Tyr(tBu)-OH (5mM) forms sphere-like assemblies at room temperature which may be converted to fibers-like structure on heating at 70 0C. In the case of Fmoc-D-Tyr(tBu)-OH, it formed a destructive aggregate at lower concentration instated of fibrils structure.

benefits

Taking Fmoc-D-Tyr(tBu)-OH can have an impact on the regulatory effects of mental, physical, metabolic, skin, growth rate, and psychology. It mainly has a good improvement effect on long-term fatigue, drowsiness, boredom, depression, frigidity, allergic reactions (allergies), headaches, anti-hunger, anti ultraviolet radiation, weight loss, blood pressure, Parkinson's disease, memory enhancement, attention deficit disorder, dementia, benzophenone medication, hangover, and mental stimulation in people

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