GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemical Properties

Melting point:

>240°C (dec.)

storage temp. 

-20°C

solubility 

H₂O: 50 mg/mL

form 

powder

color 

white

BRN 

6467425

Safety Information

WGK Germany 

3

F 

10-21

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT Usage And Synthesis

Chemical Properties

White powder

Uses

Guanosine 3’,5’-Cyclic Monophosphate is a substituted Guanosine having cyclic phosphodiesterase activity.

Biochem/physiol Actions

An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).

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