3,6-DIAMINOACRIDINE HYDROCHLORIDE
3,6-DIAMINOACRIDINE HYDROCHLORIDE Basic information
- Product Name:
- 3,6-DIAMINOACRIDINE HYDROCHLORIDE
- Synonyms:
-
- 3,6-diaminoacridinehydrochloridehemihydrate
- 3,6-diamino-acridinmonohydrochloride
- nci-c04137
- PROFLAVINE HYDROCHLORIDE
- PROFLAVINE MONOHYDROCHLORIDE
- PROFLAVIN MONOHYDROCHLORIDE
- TIMTEC-BB SBB003182
- EUFLAVIN
- CAS:
- 952-23-8
- MF:
- C13H12ClN3
- MW:
- 245.71
- EINECS:
- 213-459-9
- Mol File:
- 952-23-8.mol
3,6-DIAMINOACRIDINE HYDROCHLORIDE Chemical Properties
- Melting point:
- 270°C (dec.) (lit.)
- storage temp.
- Inert atmosphere,Room Temperature
- EPA Substance Registry System
- Proflavine hydrochloride (952-23-8)
3,6-DIAMINOACRIDINE HYDROCHLORIDE Usage And Synthesis
Uses
Acridine-3,6-diamine hydrochloride, canbe used for studying cation transfer at the liquid–liquid interface.
Definition
ChEBI: A hydrochloride resulting from the reaction of equimolar amounts of 3,6-diaminoacridine and hydrogen chloride.
General Description
Brown powder.
Air & Water Reactions
Slightly soluble in water.
Reactivity Profile
3,6-DIAMINOACRIDINE HYDROCHLORIDE is amphoteric. Reacts both as a weak acid and as a weak base.
Safety Profile
Poison by subcutaneous route. Questionable carcinogen. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used as a drug, as a Isinfectant, and as a topical antiseptic.
Purification Methods
It is first purified by precipitation of the free base by adding aqueous NH3 solution to an aqueous solution of the hydrochloride or hydrogen sulfate (see below), drying the precipitate and subliming at 0.01mm Hg [Müller & Crothers Eur J Biochem, 54 267 1975]. [Beilstein 22 H 487.]
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