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Axitinib Sulfonyl

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Axitinib Sulfonyl Basic information

Product Name:
Axitinib Sulfonyl
Synonyms:
  • Axitinib Impurity b
  • Axitinib Sulfone
  • Axitinib Impurity 6/Axitinib Sulfone/N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]-benzamide
  • N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide
  • Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]-
  • Axitinib D
  • Axitinib Sulfonyl Impurity
  • Axitinib Sulfone Impurity
CAS:
1348536-59-3
MF:
C22H18N4O3S
MW:
418.47
Mol File:
1348536-59-3.mol
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Axitinib Sulfonyl Chemical Properties

Boiling point:
735.3±60.0 °C(Predicted)
Density 
1.393±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
10.59±0.40(Predicted)
color 
Off-White to Pale Yellow
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Axitinib Sulfonyl Usage And Synthesis

Uses

N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide (Axitinib sulfone) is an impurity of axitinib (A794650), a tyrosine kinase inhibitor and is used in cancer therapy.

Axitinib SulfonylSupplier

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