Amino-PEG8-azide Chemical Properties

storage temp. 

-20°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

solid or viscous liquid

color 

Light Yellow to Light Beige

Safety Information

HS Code 

2942000090

Amino-PEG8-azide Usage And Synthesis

Description

Azido-dPEG₇-amine is a heterobifunctional PEGylated linker. It contains a reactive NH₂ end group, as well as an azide functional group for use in click chemistry reactions. Azido-dPEG₇-amine has been used as a linker in the synthesis of bivalent mammalian target of rapamycin (mTOR) inhibitors.

Uses

Azido-PEG7-amine is used in methods for detecting assay interferences and increasing dynamic range.

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry

IC 50

Non-cleavable Linker; PEGs

References

[1] GOSWAMI L N, HOUSTON Z H, SARMA S J, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery?[J]. Organic & Biomolecular Chemistry, 2012, 7: 1116-1126. DOI: 10.1039/c2ob26968f
[2] VANESSA S. RODRIK-OUTMEZGUINE. Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor[J]. Nature, 2016, 534 7606: 272-276. DOI: 10.1038/nature17963

Amino-PEG8-azide(1333154-77-0)Related Product Information

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