Febuxostat Impurity 14 Chemical Properties

Melting point:

84-86°C

Boiling point:

435.5±55.0 °C(Predicted)

Density 

1.17±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer, Under inert atmosphere

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

pka

2.48±0.10(Predicted)

form 

Solid

color 

Off-White to Pale Pink

InChI

InChI=1S/C15H16N2OS/c1-10(2)8-18-14-5-4-12(6-13(14)7-16)15-17-11(3)9-19-15/h4-6,9-10H,8H2,1-3H3

InChIKey

SZCKORPTGMXHLL-UHFFFAOYSA-N

SMILES

C(#N)C1=CC(C2=NC(C)=CS2)=CC=C1OCC(C)C

Febuxostat Impurity 14 Usage And Synthesis

Uses

Descarboxyl Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout.

Febuxostat Impurity 14(1335202-60-2)Related Product Information

• Febuxostat
• Febuxostat Acyl-β-D-glucuronide
• 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide
• 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid
• 2-(4-HYDROXY-PHENYL)-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID
• ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5- carboxylate
• FeBuxostat Impurity 32
• 2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid
• Febuxostat Bromo Impurity
• 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
• 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid
• ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5- carboxylate
• FeBuxostat Impurity 18
• ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate
• 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid
• Febuxostat impurity 37
• FeBuxostat Impurity 33
• Febuxostat Descyano Impurity