Ald-Ph-PEG2-t-butyl ester Chemical Properties

Boiling point:

547.6±45.0 °C(Predicted)

Density 

1.132±0.06 g/cm3(Predicted)

storage temp. 

2-8°C, stored under nitrogen

solubility 

Soluble in DMSO, DCM, DMF

pka

13.53±0.46(Predicted)

form 

Viscous Liquid

color 

Colorless to light yellow

Ald-Ph-PEG2-t-butyl ester Usage And Synthesis

Description

Ald-Ph-PEG2-t-butyl ester is reactive with aminooxy containing molecules The t-butyl ester can be removed under acidic conditions.

Uses

Ald-Ph-amido-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Ald-Ph-PEG2-t-butyl ester(1807521-09-0)Related Product Information

• Ald--Ph-PEG3-amine
• Ald-Ph-PEG4-t-butyl ester
• Acid-PEG4-t-butyl ester
• Ald--Ph-PEG2-acid
• Ald-Ph-PEG4-acid
• Ald-PEG4-t-butyl ester
• Acid-PEG3-t-butyl ester
• Acid-PEG6-t-butyl ester
• Ald-PEG5-t-butyl ester
• Acid-PEG5-t-butyl ester
• Ald-Ph-PEG2-amine
• m-PEG4-benzaldehyde
• Ald--Ph-PEG2-NHS
• Ald-PEG4-NHS ester
• Ald-Ph-PEG6-t-butyl ester
• Ald-Ph-PEG3-Azide
• m-PEG4-CH2-aldehyde
• Ald-PEG5-Azide