Amino-PEG9-Amine Chemical Properties

Boiling point:

527.4±45.0 °C(Predicted)

Density 

1.078±0.06 g/cm3(Predicted)

storage temp. 

2-8°C, protect from light

form 

Liquid

pka

9.04±0.10(Predicted)

color 

Colorless to light yellow

Amino-PEG9-Amine Usage And Synthesis

Description

Amino-PEG9-Amine is a PEG linker containing two amine functional groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

Uses

Amino-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Amino-PEG9-Amine(474082-35-4)Related Product Information

• 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester
• H2N-PEG13-CH2CH2NH2
• Amino-PEG11-Amine
• O,O′-Bis(2-aMinoethyl)polyethylene Glycol
• 3,6,9,12,15,21,24,27,30-Decaoxadotriacontane-1,32-diaMine
• H2N-PEG12-CH2CH2NH2
• 3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AMINE
• 3,6,9-trioxaundecamethylenediamine
• 3,6,9,12,15,18,21,24-Octaoxahexacosane-1,26-diamine
• Amino-PEG15-azide
• alpha-aMine-oMega-propionic acid octaethylene glycol
• Amino-PEG15-alcohol
• 1,14-diamino-3,6,9,12-tetraoxatetradecane
• Amino-PEG7-acid
• 3,6,9,12,15,18-Hexaoxaeicosane-1,20-diamine
• Amino-PEG6-t-butyl acetate
• alpha-aMine-oMega-propionic acid dodecaethylene glycol
• Amino-PEG5-acid