Azido-PEG3-aldehyde Chemical Properties

form 

Liquid

color 

Colorless to off-white

Azido-PEG3-aldehyde Usage And Synthesis

Biological Activity

Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Azido-PEG3-aldehyde(1807530-10-4)Related Product Information

• Ald-PEG3-Azide
• Azido-PEG6-CH2COOH
• Azide-PEG3-Desthiobiotin
• Azido-PEG16-acid
• Azido-PEG3-Tos
• Azido-PEG15-azide
• Azido-PEG15-alcohol
• Azido-PEG16-t-butyl ester