Biotin-PEG2-C6-Azide Chemical Properties

storage temp. 

Storage temp. 2-8°C

form 

Solid

color 

White to off-white

Biotin-PEG2-C6-Azide Usage And Synthesis

Description

Biotin-PEG2-C6-azide is PEG linker containing a biotin group and an azide group. The azide group can react with either alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The spacer arm helps to minimize steric hindrance involved with the binding to avidin molecules.

Uses

Biotin-PEG2-C6-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Biotin-PEG2-C6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

Biotin-PEG2-C6-Azide(1011268-29-3)Related Product Information

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• Bis-sulfone-PEG3-Azide
• Cy3 azide
• 6-Azido-hexanoic acid
• Cy5 Azide
• Biotin-PEG2-C4-Alkyne
• (3aS,4S,6aR)-Hexahydro-2-oxo-N-(15-oxo-3,6,9,12-tetraoxa-16-azanonadec-18-yn-1-yl)-1H-thieno[3,4-d]imidazole-4-pentanamide
• Mal-PEG3-Mal
• Biotin-PEG2-SH
• 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[2-(2-hydroxyethoxy)ethyl]-2-oxo-, (3aS,4S,6aR)-
• Biotin-PEG2-Hydrazide
• Azidoacetic acid