Hydroxy-PEG3-PFP ester
Hydroxy-PEG3-PFP ester Basic information
- Product Name:
- Hydroxy-PEG3-PFP ester
- Synonyms:
-
- Hydroxy-PEG3-PFP ester
- Hydroxy-PEG3-C2-PFP ester
- Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
- CAS:
- 1807537-40-1
- MF:
- C15H17F5O6
- MW:
- 388.28
- Mol File:
- 1807537-40-1.mol
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Hydroxy-PEG3-PFP ester Chemical Properties
- Boiling point:
- 440.3±45.0 °C(Predicted)
- Density
- 1.385±0.06 g/cm3(Predicted)
- pka
- 14.36±0.10(Predicted)
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Hydroxy-PEG3-PFP ester Usage And Synthesis
Biological Activity
Hydroxy-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Hydroxy-PEG3-PFP esterSupplier
Jinan elephant international trading co., LTD
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- 13006575422@163.com
Xi'an Confluore Biological Technology Co., Ltd.
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- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
Alpha Biopharmaceuticals Co., Ltd
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- 0411-39042497
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TargetMol Chemicals Inc.
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- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
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- 029-86217788 13892832556
- 2440688701@qq.com
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