Tos-PEG6-t-Butyl ester
Tos-PEG6-t-Butyl ester Basic information
- Product Name:
- Tos-PEG6-t-Butyl ester
- Synonyms:
-
- Tos-PEG5-CH2CH2COOtBu
- Tos-PEG6-t-Butyl ester
- Tos-PEG5-C2-Boc
- 4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
- tert-butyl 1-(tosyloxy)-3,6,9,12,15-pentaoxaoctadecan-18-oate
- 3,6,9,12,15-Pentaoxaoctadecan-18-oic acid,1-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
- Tos-PEG5-CH2CH2COOtBu/4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
- tert-butyl 3-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
- CAS:
- 850090-10-7
- MF:
- C24H40O10S
- MW:
- 520.63
- Mol File:
- 850090-10-7.mol
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Tos-PEG6-t-Butyl ester Chemical Properties
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
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Tos-PEG6-t-Butyl ester Usage And Synthesis
Description
Tos-PEG6-t-Butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
Uses
Tos-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
Alkyl/ether; PEGs
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.
Tos-PEG6-t-Butyl esterSupplier
Nanjing Junnahe Biopharmaceutical Co., Ltd
- Tel
- 025-58367986 17351780683
- amy.xiang@ally-chem.com
Jinan elephant international trading co., LTD
- Tel
- 13006575422@163.com
Shanghai Yihe Biological Technology Co., Ltd.
- Tel
- 021-68882955 17721395025
- 2423903095@qq.com
Amatek Scientific Co. Ltd.
- Tel
- 0512-56316828
- info@amateksci.com
Aikon International Limited
- Tel
- 025-58851090 15955137747
- sales01@aikonchem.com
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Tos-PEG6-t-Butyl ester(850090-10-7)Related Product Information
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