2-(4-hydroxy-1H-indol-3-yl)acetic acid Chemical Properties

Boiling point:

497.1±30.0 °C(Predicted)

Density 

1.496±0.06 g/cm3(Predicted)

solubility 

DMF: 25 mg/ml
DMSO: 25 mg/ml
Ethanol: 25 mg/mlPBS (pH 7.2): 0.1 mg/ml

pka

4.42±0.30(Predicted)

form 

Solid

2-(4-hydroxy-1H-indol-3-yl)acetic acid Usage And Synthesis

Uses

2-(4-Hydroxy-1H-indol-3-yl)acetic Acid can be useful in the development and validation of an LC-MS/MS method for the bioanalysis of psilocybins main metabolites, psilocin and 4-hydroxyindole-3-acetic acid, in human plasma.

References

[1] KAROLINA E. KOLACZYNSKA  Urs D  Matthias E Liechti. Development and validation of an LC-MS/MS method for the bioanalysis of psilocybin’s main metabolites, psilocin and 4-hydroxyindole-3-acetic acid, in human plasma[J]. Journal of Chromatography B, 2021, 1164: Article 122486. DOI: 10.1016/j.jchromb.2020.122486
[2] TORSTEN PASSIE. The pharmacology of psilocybin[J]. Addiction Biology, 2006, 7 4: 357-364. DOI: 10.1080/1355621021000005937

2-(4-hydroxy-1H-indol-3-yl)acetic acid(56395-08-5)Related Product Information

• 2,4-Imidazolidinedione, 5-(1H-indol-3-ylmethyl)-, (5R)-
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• Tryptophan Impurity 3
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