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Diquafosol Impurity 1

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Diquafosol Impurity 1 Basic information

Product Name:
Diquafosol Impurity 1
Synonyms:
  • Diquafosol Impurity 4(UP2U)
  • Diquafosol Impurity 2
  • Diquafosol Impurity 3
  • Diuridine diphosphate
  • Uridine 5'-(trihydrogen diphosphate), P'→5'-ester with uridine
  • α-UTP
  • Up2U / UppU
  • Uridine 5'-(trihydrogen pyrophosphate), 5'→5'-ester with Uridine
CAS:
26184-65-6
MF:
C18H24N4O17P2
MW:
630.35
EINECS:
604-604-1
Mol File:
26184-65-6.mol
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Diquafosol Impurity 1 Chemical Properties

Density 
1.907±0.06 g/cm3(Predicted)
pka
0.83±0.50(Predicted)
InChIKey
NYKBJLRPFUFPAX-BTTIJRIRNA-N
SMILES
O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@H](N3C=CC(=O)NC3=O)O2)O)O[C@H]1N1C=CC(=O)NC1=O)O |&1:1,2,3,15,16,17,19,31,r|
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Diquafosol Impurity 1 Usage And Synthesis

Uses

P1,P2-Diuridine-5’-diphosphate (Up2U) is a symmetrical dinucleoside polyphosphate containing two pyrimidine base moieties. P1,P2-Diuridine-5’-diphosphate is also an activator of purinergic P2Y receptor[1].

References

[1] Hall, Ross H, et al. Nucleoside Polyphosphates. III. 1 Syntheses of Pyrimidine Nucleoside-2'(3'), 5'-diphosphates. Journal of the American Chemical Society 77.7 (1955): 1871-1875.

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