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tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate

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tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate Basic information

Product Name:
tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate
Synonyms:
  • tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate
  • EOS-60599
  • TERT-BUTYL N-[(4-BROMO-5-CYANO-1-METHYL-1H-PYRAZOL-3-YL)METHYL]-N-METHYLCARBAMATE
  • Carbamic acid, N-[(4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl]-N-methyl-, 1,1-dimethylethyl ester
  • tert-butyl N-[(4-bromo-5-cyano-1-methylpyrazol-3-yl)methyl]-N-methylcarbamate
  • 1-methyl-3-[(N-methyl-N-boc-amino)methyl]-1H-pyrzole-5-methannitrile
  • ert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate
CAS:
1454848-24-8
MF:
C12H17BrN4O2
MW:
329.19
Mol File:
1454848-24-8.mol
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tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate Chemical Properties

Boiling point:
441.1±45.0 °C(Predicted)
Density 
1.38±0.1 g/cm3(Predicted)
storage temp. 
Store at 0-8 °C
pka
-1.77±0.70(Predicted)
InChI
InChI=1S/C12H17BrN4O2/c1-12(2,3)19-11(18)16(4)7-8-10(13)9(6-14)17(5)15-8/h7H2,1-5H3
InChIKey
XXLRKGVZBYVBNQ-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)N(CC1C(Br)=C(C#N)N(C)N=1)C
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tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate Usage And Synthesis

Uses

tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate is a pharmaceutical intermediate compound that can be used in the synthetic anticancer prescription drug Lorlatinib. Lorlatinib is a drug used in the treatment of non-small cell lung cancer caused by adult non-small cell lung cancer (NSCLC) caused by an unusual mesenchymal lymphoma.

tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamateSupplier

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tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate(1454848-24-8)Related Product Information