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Peptide 5

Basic information Safety Supplier Related

Peptide 5 Basic information

Product Name:
Peptide 5
Synonyms:
  • Peptide 5
  • L-Threonine, L-valyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-leucyl-L-seryl-L-arginyl-L-prolyl-L-threonyl-L-α-glutamyl-L-lysyl-
  • Peptide 5 trifluoroacetate salt
CAS:
916977-43-0
MF:
C60H98N16O20S
MW:
1395.6
Mol File:
916977-43-0.mol
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Peptide 5 Chemical Properties

Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
3.22±0.10(Predicted)
InChIKey
RJEAEIUDNCLZNN-HXDGCKLRNA-N
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Peptide 5 Usage And Synthesis

Description

Peptide5 is a connexin43 mimetic peptide. Reduces swelling, astrogliosis, neuroinflammation and neuronal cell death following spinal cord injury ex vivo and in vivo. Exhibits analgesic effects in models of neuropathic pain.

in vitro

Peptide5, significantly reduces the degree of spinal cord injury (SCI) in a rodent ex vivo model. Peptide5 produces the more significant reduction in swelling and is analyzed further. Treatment with peptide5 reduced both the level of Cx43 and the number of glial fibrillary acidic protein (GFAP)-positive astrocytes, and at the same time reduces the loss of NeuN- and SMI-32–positive neurons in a concentration- and time-dependent manner.

Peptide 5Supplier

Creative Peptides
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Email
info@creative-peptides.com
Beijing Solarbio Science & Tecnology Co., Ltd.
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010-50973130 4009686088
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3193328036@qq.com
Hangzhou Peptidego Biotech Co.,Ltd.
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0571-87213919
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eric@peptidego.com
Shanghai Hongye Biotechnology Co. Ltd
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400-9205774
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sales@glpbio.cn
BOC Sciences
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+16314854226
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inquiry@bocsci.com