Peptide 5
Peptide 5 Basic information
- Product Name:
- Peptide 5
- Synonyms:
-
- Peptide 5
- L-Threonine, L-valyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-leucyl-L-seryl-L-arginyl-L-prolyl-L-threonyl-L-α-glutamyl-L-lysyl-
- Peptide 5 trifluoroacetate salt
- CAS:
- 916977-43-0
- MF:
- C60H98N16O20S
- MW:
- 1395.6
- Mol File:
- 916977-43-0.mol
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Peptide 5 Chemical Properties
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 3.22±0.10(Predicted)
- InChIKey
- RJEAEIUDNCLZNN-HXDGCKLRNA-N
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Peptide 5 Usage And Synthesis
Description
Peptide5 is a connexin43 mimetic peptide. Reduces swelling, astrogliosis, neuroinflammation and neuronal cell death following spinal cord injury ex vivo and in vivo. Exhibits analgesic effects in models of neuropathic pain.
in vitro
Peptide5, significantly reduces the degree of spinal cord injury (SCI) in a rodent ex vivo model. Peptide5 produces the more significant reduction in swelling and is analyzed further. Treatment with peptide5 reduced both the level of Cx43 and the number of glial fibrillary acidic protein (GFAP)-positive astrocytes, and at the same time reduces the loss of NeuN- and SMI-32–positive neurons in a concentration- and time-dependent manner.
Peptide 5Supplier
Creative Peptides
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- info@creative-peptides.com
Beijing Solarbio Science & Tecnology Co., Ltd.
- Tel
- 010-50973130 4009686088
- 3193328036@qq.com
Chengdu Youngshe Chemical Co., Ltd.
- Tel
- +86-17380623303 +86-17380623303
- Caroline@youngshechem.com
Hangzhou Peptidego Biotech Co.,Ltd.
- Tel
- 0571-87213919
- Eric@peptidego.com
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn