Dolutegravir Impurity 8 Chemical Properties

Boiling point:

304.9±42.0 °C(Predicted)

Density 

1.22±0.1 g/cm3(Predicted)

pka

3.22±0.50(Predicted)

Dolutegravir Impurity 8 Usage And Synthesis

Uses

N-[(2,4-Difluorophenyl)methylene]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D450850), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.

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