Basic information Safety Supplier Related

Etelcalcetide

Basic information Safety Supplier Related

Etelcalcetide Basic information

Product Name:
Etelcalcetide
Synonyms:
  • Etelcalcetide
  • D-Argininamide, N-acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-, disulfide with L-cysteine
  • AMG-416 (Velcalcetide)
  • Parsavib
  • S-(((S)-2-Acetamido-3-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-amino-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-oxopropyl)thio)-L-cysteine
CAS:
1262780-97-1
MF:
C38H73N21O10S2
MW:
1048.25
Mol File:
1262780-97-1.mol
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Etelcalcetide Chemical Properties

Density 
1.58±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
2.01±0.10(Predicted)
Sequence
H-Cys(1)-OH,Ac-D-Cys(1)-D-Ala-D-Arg-D-Arg-D-Arg-D-Ala-D-Arg-NH2(Disulfide bridge Cys1-(D-Cys1))/C(1),Ac-(D-C(1)-(D-A)-(D-R)-(D-R)-(D-R)-(D-A)-(D-R)-NH2(Disulfide bridge Cys1-(D-Cys1))
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Etelcalcetide Usage And Synthesis

Uses

N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl- D-Argininamide-L-cysteine Disulfide is a useful research chemical used in the treatment of chronic kidney disease-??mineral and bone disorder.

Definition

ChEBI: Etelcalcetide is an oligopeptide.

Clinical Use

Synthetic peptide calcimimetic agent:
Treatment of secondary hyperparathyroidism in patients on haemodialysis

Drug interactions

Potentially hazardous interactions with other drugs
Avoid with cinacalcet.

Metabolism

Etelcalcetide is biotransformed in blood by reversible disulphide exchange with endogenous thiols to predominantly form conjugate with serum albumin

EtelcalcetideSupplier

Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Email
sales@sunlidabio.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Email
sales@reading-chemicals.com
Hangzhou Peptide Biochem Co.,Ltd
Tel
0571-89197072; 18668118770
Email
linda@peptide-china.com
Creative Peptides
Tel
Email
info@creative-peptides.com
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com