Etelcalcetide
Etelcalcetide Basic information
- Product Name:
- Etelcalcetide
- Synonyms:
-
- Etelcalcetide
- D-Argininamide, N-acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-, disulfide with L-cysteine
- AMG-416 (Velcalcetide)
- Parsavib
- S-(((S)-2-Acetamido-3-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-amino-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-oxopropyl)thio)-L-cysteine
- CAS:
- 1262780-97-1
- MF:
- C38H73N21O10S2
- MW:
- 1048.25
- Mol File:
- 1262780-97-1.mol
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Etelcalcetide Chemical Properties
- Density
- 1.58±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 2.01±0.10(Predicted)
- Sequence
- H-Cys(1)-OH,Ac-D-Cys(1)-D-Ala-D-Arg-D-Arg-D-Arg-D-Ala-D-Arg-NH2(Disulfide bridge Cys1-(D-Cys1))/C(1),Ac-(D-C(1)-(D-A)-(D-R)-(D-R)-(D-R)-(D-A)-(D-R)-NH2(Disulfide bridge Cys1-(D-Cys1))
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Etelcalcetide Usage And Synthesis
Uses
N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl- D-Argininamide-L-cysteine Disulfide is a useful research chemical used in the treatment of chronic kidney disease-??mineral and bone disorder.
Definition
ChEBI: Etelcalcetide is an oligopeptide.
Clinical Use
Synthetic peptide calcimimetic agent:Treatment of secondary hyperparathyroidism in patients on haemodialysis
Drug interactions
Potentially hazardous interactions with other drugs Avoid with cinacalcet.
Metabolism
Etelcalcetide is biotransformed in blood by reversible disulphide exchange with endogenous thiols to predominantly form conjugate with serum albumin
EtelcalcetideSupplier
Nanjing Sunlida Biological Technology Co., Ltd.
- Tel
- 025-57798810
- sales@sunlidabio.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
- Tel
- 0510-85629785 18013409632
- sales@reading-chemicals.com
Hangzhou Peptide Biochem Co.,Ltd
- Tel
- 0571-89197072; 18668118770
- linda@peptide-china.com
Creative Peptides
- Tel
- info@creative-peptides.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
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