(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Chemical Properties

Boiling point:

302.6±35.0 °C(Predicted)

Density 

1.00±0.1 g/cm3(Predicted)

pka

10.26±0.40(Predicted)

(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Usage And Synthesis

Uses

(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an intermediate in the synthesis of (3R,4S)-Tofacitinib (T528000). (3R,4S)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.

(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine(1638499-31-6)Related Product Information

• 4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine
• N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine oxide
• 2,4-DICHLORO-7H-PYRROLO2,3-DPYRIMIDINE
• 3-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyriMidin-4-yl)(Methyl)aMino)-4-Methylpiperidin-1-yl)-3-oxopropanenitrile
• 4-METHYL-3-METHYLAMINOPYRIDINE
• 3-Piperidinamine,4-methyl-1-(phenylmethyl)-,(3R,4R)-rel-
• Tofacitinib impurity T
• N-Hydroxysuccinimide
• 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
• methyl3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin -4-yl)amino)piperidin-1-yl)-3-oxopropanoate
• Methyl (4-Methylpiperidin-3-yl)carbaMate
• 3-((3S,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile
• (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride
• 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile
• 1-Piperidinepropanoic acid, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, ethyl ester, (3R,4R)-
• (3R,4R)-N,4-dimethyl-piperidin-3-amine
• 3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
• CYANOACETIC ACID-OSU