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Rivaroxaban Impurity 27

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Rivaroxaban Impurity 27 Basic information

Product Name:
Rivaroxaban Impurity 27
Synonyms:
  • Rivaroxaban Impurity 13/2-[(2S)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione
  • Rivaroxaban Impurity 27
  • 2-[(2S)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione
  • 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-
  • (S)-2-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione? (Rivaroxaban Impurity)
CAS:
1369969-44-7
MF:
C21H21N3O5
MW:
395.41
Mol File:
1369969-44-7.mol
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Rivaroxaban Impurity 27 Chemical Properties

Boiling point:
734.9±60.0 °C(Predicted)
Density 
1.421±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
13.91±0.20(Predicted)
color 
White to Off-White
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Rivaroxaban Impurity 27 Usage And Synthesis

Uses

2-[(2S)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione is an intermediate in the synthesis of ent-Rivaroxaban (R538005), the R-isomer of Rivaroxaban (R538000), which is a novel antithrombotic agent.

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