Basic information Safety Supplier Related

Propargyl-PEG4-Sulfone-PEG4-t-butyl ester

Basic information Safety Supplier Related

Propargyl-PEG4-Sulfone-PEG4-t-butyl ester Basic information

Product Name:
Propargyl-PEG4-Sulfone-PEG4-t-butyl ester
Synonyms:
  • Propargyl-PEG4-Sulfone-PEG4-t-butyl ester
  • Propargyl-PEG4-Sulfone-PEG4-Boc
  • 4,7,10,13,19,22,25,28-Octaoxa-16-thiahentriacont-30-ynoic acid, 1,1-dimethylethyl ester, 16,16-dioxide
CAS:
2055024-43-4
MF:
C26H48O12S
MW:
584.72
Mol File:
2055024-43-4.mol
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Propargyl-PEG4-Sulfone-PEG4-t-butyl ester Chemical Properties

Boiling point:
647.7±55.0 °C(Predicted)
Density 
1.131±0.06 g/cm3(Predicted)
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Propargyl-PEG4-Sulfone-PEG4-t-butyl ester Usage And Synthesis

Description

Propargyl-PEG4-Sulfone-PEG4-t-butyl ester is a PEG linker containing a propargyl group and t-butyl protected carboxyl group acid. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The t-butyl protected carboxyl group (COOH) prevents self coupling or polymerization under standard acid/amine or acid/hydroxyl coupling conditions. The protected acid can be deprotected by acidic or basic hydrolysis. The hydrophilic PEG spacer increases solubility in aqueous media.

Propargyl-PEG4-Sulfone-PEG4-t-butyl esterSupplier

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