3-Iodoaniline Chemical Properties

Melting point:

21-24 °C (lit.)

Boiling point:

145-146 °C/15 mmHg (lit.)

Density 

1.821 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.682(lit.)

Flash point:

>230 °F

storage temp. 

2-8°C

form 

liquid (clear)

pka

3.58(at 25℃)

Specific Gravity

1.820

color 

clear yellow

Water Solubility 

Insoluble in water.

Sensitive 

Light Sensitive

BRN 

636058

InChIKey

FFCSRWGYGMRBGD-UHFFFAOYSA-N

CAS DataBase Reference

626-01-7(CAS DataBase Reference)

NIST Chemistry Reference

3-I-C6H4NH2(626-01-7)

EPA Substance Registry System

m-Iodoaniline (626-01-7)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-37/38-36/37/38

Safety Statements 

36/37-36/37/39-26-36

RIDADR 

2810

WGK Germany 

3

RTECS 

BY3750000

F 

8

TSCA 

T

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29214210

MSDS

• Language:English Provider:3-Iodoaniline
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Iodoaniline Usage And Synthesis

Chemical Properties

Clear colorless to yellow-brown low melting solid

Uses

3-Iodoanilineis used as Anilines, Aromatic Amines and Nitro Compounds.

Synthesis Reference(s)

Tetrahedron Letters, 34, p. 3083, 1993 DOI: 10.1016/S0040-4039(00)93385-9

Synthesis

The general procedure for the synthesis of 3-iodoaniline from 1-iodo-3-nitrobenzene was carried out as follows: the TAPEHA-Pd catalyst (0.015 g) was added to a mixture of EtOH/water (1:1, 20 mL) containing nitroaromatics (1.0 mmol). Upon slow addition of NaBH4 (4.0 mmol), the color of the reaction mixture gradually changed to black within a few minutes, indicating the formation of palladium nanoparticles (TAPEHA-PdNPs). The reaction was stirred continuously for 1.5 h at room temperature and atmospheric pressure. After completion of the reaction, the catalyst was removed by filtration. The product in the reaction mixture was extracted with ethyl acetate (3 × 30 mL). The organic layers were combined and dried with anhydrous MgSO4 and subsequently concentrated under vacuum.

References

[1] Nature Chemistry, 2013, vol. 5, # 6, p. 537 - 543
[2] Dalton Transactions, 2016, vol. 45, # 17, p. 7421 - 7426
[3] Turkish Journal of Chemistry, 2017, vol. 41, # 5, p. 784 - 792
[4] Tetrahedron Letters, 1994, vol. 35, # 23, p. 3965 - 3966
[5] Synthetic Communications, 2003, vol. 33, # 2, p. 281 - 289

3-Iodoaniline(626-01-7)Related Product Information

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