(-)-ECG-3''-O-ME
(-)-ECG-3''-O-ME Basic information
- Product Name:
- (-)-ECG-3''-O-ME
- Synonyms:
-
- (-)-EPICATECHIN 3-(3''-O-METHYL)GALLATE
- (-)-ECG-3''-O-ME
- 3,4-Dihydroxy-5-methoxy-benzoic acid (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester
- Epicatechin 3-O-(3-O-methyl)gallate
- (-)-Epicatechin 3-(3''-O-Methyl)gallate (natural) 〔(-)-ECg-3''-O-Me〕
- (-)-Epicatechin 3-(3''-O-Methyl)gallate 〔(-)-ECg-3''-O-Me〕
- Benzoic acid,3,4-dihydroxy-5-methoxy-,(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-ylester
- (-)-Epicatechin-3-(3''-O-methyl) gallate
- CAS:
- 83104-86-3
- MF:
- C23H20O10
- MW:
- 456.4
- Mol File:
- 83104-86-3.mol
(-)-ECG-3''-O-ME Chemical Properties
- Melting point:
- 248-250℃ (decomposition)
- Boiling point:
- 812.9±65.0 °C(Predicted)
- Density
- 1.69±0.1 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 7.92±0.25(Predicted)
(-)-ECG-3''-O-ME Usage And Synthesis
Uses
(-)-Epicatechin 3-(3-O-methylgallate) is a catechin, that can be isolated from tea leaf. (-)-Epicatechin 3-(3-O-methylgallate) shows anti-inflammatory activity[1][2].
Definition
ChEBI: Epicatechin 3-O-(3'-O-methylgallate) is a gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3R)-hydroxy group of epicatechin. It has a role as a Camellia sinensis metabolite and an anti-inflammatory agent. It is a member of flavans, a gallate ester, a polyphenol and a monomethoxybenzene. It is functionally related to a (-)-epicatechin.
References
[1] Saijo R . Isolation and Chemical Structures of Two New Catechins from Fresh Tea Leaf[J].Agricultural and Biological Chemistry, 1982.
[2] Iijima T, et al. Synthesis of (-)-epicatechin 3-(3-O-methylgallate) and (+)-catechin 3-(3-O-methylgallate), and their anti-inflammatory activity. Chem Biodivers. 2009 Apr;6(4):520-6. DOI:10.1002/cbdv.200800224
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